摘要
目的 分析盐酸氨溴索用于老年慢阻肺(COPD)合并肺感染的临床意义。方法 选取我院老年病二科收治的老年COPD患者64例,随机分为参照组和实验组各32例,两组均进行常规治疗,参照组在此基础上采用溴已新葡萄糖注射液治疗,实验组采用盐酸氨溴索治疗,观察两组患者治疗效果。结果 经对比,实验组患者的临床症状消失时间、肺功能指标以及血气指标均优于对照组(P<0.05),参照组和实验组治疗总有效率分别为68.75%和96.87%,实验组高于参照组(P<0.05),且参照组不良反应总发生率多于实验组(P<0.05)。结论 老年COPD合并肺感染患者采用盐酸氨溴索治疗疗效显著,能够有效缩短患者临床症状消失时间,改善患者肺功能和血气指标,减少不良反应的发生,从而提高了治疗效率。
关键词: 盐酸氨溴索;老年COPD;肺感染;临床疗效;肺功能
Abstract
Objective To analyze the clinical significance of ambroxol hydrochloride in elderly patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary infection. Methods A total of 64 elderly COPD patients admitted to the Second Department of Geriatrics in our hospital were selected and randomly divided into a reference group and an experimental group with 32 cases in each group. Both groups received conventional treatment. On this basis, the reference group was treated with bromhexine glucose injection. The experimental group was treated with ambroxol hydrochloride, and the therapeutic effect of the two groups was observed. Results After comparison, the clinical symptoms disappearance time, pulmonary function indexes and blood gas indexes of the experimental group were better than those of the control group (P<0.05). Compared with the reference group (P<0.05), the total incidence of adverse reactions in the reference group was higher than that in the experimental group (P<0.05). Conclusion Ambroxol hydrochloride is effective in the treatment of elderly patients with COPD complicated with pulmonary infection, which can effectively shorten the disappearance time of clinical symptoms, improve the pulmonary function and blood gas indexes, and reduce the occurrence of adverse reactions, thereby improving the treatment efficiency.
Key words: Ambroxol Hydrochloride; Elderly COPD; Pulmonary Infection; Clinical Efficacy; Pulmonary Function
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