Research progress of fecal bacteria transplantation in the treatment of inflammatory bowel disease
粪菌移植治疗炎症性肠病的研究进展

摘要

粪菌移植（FMT），又称粪便微生物移植，是一种将健康人粪便中肠道菌群通过不同途径移植到患者肠道内，希望重建患者肠道菌群来达到治疗疾病目的。炎症性肠病（IBD）是一种以肠道菌群失调的非特异性肠道炎性疾病。近年来，随着对FMT认识不断加深，人们逐渐发现FMT与多种肠道菌群失调疾病密切相关，其中最吸引人眼球的是FMT对IBD的病理生理过程中发挥着重要作用。本文将着重从FMT对IBD作用机制、影响因素等方面做出详细的综述。

Abstract

Fecal bacteria transplantation (FMT), also known as fecal microbial transplantation, is a transplant of intestinal flora in healthy human feces into the intestines of patients through different ways, hoping to rebuild the intestinal flora of patients to achieve the purpose of treating diseases.Inflammatory bowel disease (IBD) is a non-specific intestinal inflammatory disorder of intestinal dysbiosis.In recent years, with the deepening understanding of FMT, it has gradually found that FMT is closely associated with a variety of intestinal flora disorders, among which the most eye-catching is that FMT plays an important role in the pathophysiological process of IBD. This paper will focus on a detailed review of the action mechanism and influencing factors of FMT on IBD.