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Open Access Article

International Journal of Internal Medicine. 2020; 1: (1) 5; 17-21 ; DOI: DOI:10.12208/j.ijim.20200005.

Research progress on EBV infection in children's nervous system
儿童神经系统EBV感染的研究进展

作者: 王燕 *

西安市儿童医院神经内科

*通讯作者: 王燕,单位:西安市儿童医院神经内科;

发布时间: 2019-12-05 总浏览量: 1228

摘要

Epstein-Barr病毒(Epstein-Barr Virus,EBV),简称EBV,属于疱疹病毒γ亚科嗜B淋巴细胞组群中的线性双链DNA病毒,又称人类疱疹病毒4型(Human Herpesvirus 4,HHV),是人类发现的第一个致癌病毒,属于传染性单核细胞增多症的病原体,其儿童与青少年属于感染的主要群体。本次研究对儿童神经系统的EBV感染进行研究,神经系统在出现EBV感染后的临床表现为EBV病毒性脑炎、中枢神经系统淋巴瘤以及EBV相关嗜血细胞综合征所致神经系统损伤。临床中在应对神经系统EBV感染时比较常用的治疗方法为抗病毒、糖皮质激素以及免疫球蛋白等。

关键词: 儿童;神经系统;EBV感染

Abstract

Epstein-Barr Virus (Epstein-Barr Virus, EBV), referred to as EBV, is a linear double-stranded DNA virus belonging to the herpes virus γ subfamily B lymphocyte group, also known as Human Herpesvirus 4, HHV It is the first carcinogenic virus discovered by humans and belongs to the pathogen of infectious mononucleosis. Its children and adolescents belong to the main group of infection. This study investigated the EBV infection of the nervous system in children. The clinical manifestations of the nervous system after the occurrence of EBV infection are EBV viral encephalitis, central nervous system lymphoma, and EBV-associated hematopoietic cell syndrome-induced neurological damage. The most commonly used treatment methods in clinical treatment of nervous system EBV infection are antiviral, glucocorticoid and immunoglobulin.

Key words: children; nervous system; EBV infection

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引用本文

王燕, 儿童神经系统EBV感染的研究进展[J]. 国际内科前沿杂志, 2020; 1: (1) : 17-21.