Clinical effect of clopidogrel on patients with acute angina pectoris in cardiovascular department
心血管内科急性心绞痛患者使用氯吡格雷治疗的临床效果观察

摘要

目的 对心血管内科治疗急性心绞痛患者时氯吡格雷临床治疗效果进行探讨；方法 以我院心血管内科2020年7月至2022年8月间收治的急性心绞痛患者80例为研究对象，按照入院先后顺序均分为对照组及观察组。患者入院后利用常规模式对对照组患者进行治疗，观察组患者在常规治疗基础上使用了氯吡格雷进行治疗，对两组患者治疗干预后临床效果进行对比分析，同时深入分析临床治疗心血管内科急性心绞痛患者中氯吡格雷临床效果及安全性进行探讨。结果 经过治疗后，对照组整体治疗有效率为80%，观察组整体治疗有效率为97.5%，两组相比较，观察组整体治疗有效率明显更好，差异显著，P<0.05。对照组患者治疗后不良反应发生率为35%，观察组不良反应发生率为5%，两组相比较，观察组不良反应发生率明显更低，差异显著，P<0.05。结论 在临床治疗心血管内科急性心绞痛过程中氯吡格雷具有显著治疗效果，可有效改善患者心功能水平，具有较高安全性，在临床上可大力推广。

Abstract

Objective To investigate the clinical effect of clopidogrel in the treatment of patients with acute angina pectoris in cardiovascular medicine;
Methods 80 patients with acute angina pectoris admitted to the Department of Cardiovascular Medicine of our hospital from July 2020 to August 2022 were selected as the study subjects. They were divided into control group and observation group according to the order of admission. After admission, the patients in the control group were treated with conventional mode. The patients in the observation group were treated with clopidogrel on the basis of conventional treatment. The clinical effects of the two groups of patients after treatment intervention were compared and analyzed. At the same time, the clinical effects and safety of clopidogrel in the clinical treatment of patients with acute angina pectoris in cardiovascular medicine were analyzed in depth.
Results After treatment, the overall effective rate of treatment in the control group was 80%, and that in the observation group was 97.5%. Compared with the two groups, the overall effective rate of treatment in the observation group was significantly better, with a significant difference (P<0.05). The incidence of adverse reactions after treatment in the control group was 35%, and that in the observation group was 5%. Compared with the two groups, the incidence of adverse reactions in the observation group was significantly lower, with a significant difference (P<0.05).
Conclusion   Clopidogrel has a significant therapeutic effect in the clinical treatment of acute angina pectoris in cardiovascular medicine, can effectively improve the level of cardiac function of patients, has a high safety, and can be vigorously promoted in clinical practice.