Clinicopathological and prognostic study of young patients with colorectal cancer
青年结直肠癌患者临床病理及预后观察

摘要

目的 对青年结直肠癌临床病理学特征以及预后进行探讨。方法 选择2019年1月至2021年12月间我院所收治的100例青年结直肠癌患者临床资料进行回顾性分析，同时以我院同期收治的65岁以上200例直肠癌患者临床资料进行对比，对其临床病理学特征以及出院后生存情况进行详细分析。结果 所有入选去年直肠癌患者病例年龄均值为（31.8±0.6）岁，根据单因素分析结果指示，患者肿瘤大小、分化程度、家族史、组织化分型等体现出了明显差异性，P<0.05。青年组织障碍患者5年生存率达到57%，老年组5年生存率达到54%，两组相比较无明显差异，P>0.05。结论 通过对青年组和老年组临床资料进行分析发现，两组患者在病理分期和预后方面无明显差异，由此指示，年龄在直肠癌患者预后中并不属于决定性的因素。

Abstract

Objective To investigate the clinicopathological characteristics and prognosis of colorectal cancer in young people.
Methods The process data of 100 young patients with colorectal cancer admitted to our hospital from January 2019 to December 2021 were analyzed retrospectively. At the same time, the clinical data of 200 patients over 65 years old admitted to our hospital at the same time were compared, and their clinicopathological characteristics and survival after discharge were analyzed in detail.
Results The average age of all rectal cancer patients selected last year was (31.8 ± 0.6) years old. According to the results of single factor analysis, there were significant differences in tumor size, differentiation degree, family history, tissue type, etc. (P<0.05). The 5-year survival rate of young patients with tissue disorders reached 57%, while that of the elderly group reached 56.5%. There was no significant difference between the two groups (P>0.05).
Conclusion   Through the analysis of the clinical data of the young group and the old group, there is no significant difference in pathological staging and prognosis between the two groups, which indicates that age is not a decisive factor in the prognosis of rectal cancer patients.